Vitamin or Mineral
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Physical Signs of Deficiency
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Vitamin
Overdose Side Effects
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Vitamin A
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- Hair follicle blockage with a permanent “goose-bump” appearance
- Dry, rough, skin
- Small, grayish, foamy deposits on the conjunctiva adjacent to the cornea
- Drying of the eyes and mucous membranes
- Night blindness
- Decreased immunity
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- Headache
- Birth defects
- Liver problems
- Osteoporosis and bone problems
- Central nervous system disorders
- Dry, scaly skin
- Yellow/orange skin with toxicity of betacarotene
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Vitamin D
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- Weakness of muscles
- Hypocalcemia
- Decreased bone density
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- Hypercalcemia
- Weakness
- Calcifications in the kidney and other soft tissues
- Polyuria
- Arrhythmias
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Vitamin E
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- Peripheral neuropathy
- Impaired immune system
- Ataxia, eye issues
- Red blood cell problems
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- Bleeding
- Hemorrhagic stroke
- Premature death
- Diarrhea
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Vitamin K
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- Small hemorrhages in the skin or mucous membranes
- Bleeding
- Decreased bone density
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- Blood clots
- Impairs action of anticoagulants
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Vitamin B1 (Thiamine)
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- Weight loss
- Muscular wasting
- Sometimes edema (wet beriberi)
- Malaise
- Tense calf muscles
- Distended neck veins
- Jerky movement of eyes
- Staggering gait and difficulty walking
- Round, swollen (moon) face
- Foot and wrist drop
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- No toxicity risk as been determined
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Vitamin B2 (Riboflavin)
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- Tearing, burning, and itching of the eyes with fissuring in the corners of the eyes
- Soreness and burning of the lips, mouth, and tongue with fissuring and/or cracking of the lips and corners of the mouth
- Purple swollen tongue
- Seborrhea of the skin in the nasolabial folds, scrotum, or vulva
- Capillary overgrowth around the corneas
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- No toxicity risk as been determined
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Vitamin B3
(Niacin)
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- Dermatitis or skin eruptions
- Tremors
- Sore tongue
- Skin that is exposed to sunlight will develop cracks and a scaly form of dermatitis with pigmentation
- May also show signs of riboflavin deficiency
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- Stomach pain
- Flushing
- Yellow skin (jaundice)
- Blurred vision
- Hyperglycemia
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Vitamin B6 (Pyridoxine)
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- Tongue inflammation
- Inflammation of the lining of the mouth
- Fissures in the corners of the mouth
- Microcytic anemia
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- Peripheral neuropathy
- Sensory ataxia, impairment of sensation of vibrations
- Decreased sense of touch, temperature, and pain
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Folate
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- Weakness, fatigue, and depression
- Change in skin, hair and fingernail pigmentation
- Dermatologic lesions
- Megaloblastic anemia
- Soreness and ulcerations in the tongue and oral mucosa
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- Provokes seizures in those taking anti-convulsion medications
- Masks vitamin B12 deficiency
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Vitamin B12 (Cobalamin)
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- Smooth, red, thickened tongue
- Megaloblastic anemia, fatigue, weakness
- Numbness and tingling of extremities
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- No toxicity risk as been determined
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Vitamin C
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- Impaired wound healing
- Edema
- Swollen, bleeding, and/or retracted gums or tooth loss; mottled teeth; enamel erosion
- Lethargy and fatigue
- Skin lesions
- Small red or purplish pinpoint discolorations on the skin or mucous membranes (petechiae)
- Darkened skin around the hair follicles
- Corkscrew hair or unemerged, coiled hair
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- Acidic urine, nausea, and diarrhea
- Impaired antioxidant-prooxidant balance in the body
- Iron overload in patients with thalassemia or hemochromatosis
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Iron
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- Skin pallor
- Pale conjuctivia
- Fatigue
- Thin, concave nails with raised edges
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- Nausea/vomiting/diarrhea
- Difficulty breathing
- Vertigo
- Headache
- Appetite loss
- Grey color to skin
- High doses may interact with calcium and zinc
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Zinc
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- Delayed wound healing
- Hair loss
- Skin lesions
- Eye lesions
- Nasolabial seborrhea
- Impaired growth
- Appetite loss, taste changes
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- General body pain
- Vomiting/diarrhea/nausea
- Fever
- Metallic taste
- No urine output
- Shortness of breath
- High doses may interact with iron and copper
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Copper
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- Hair and skin depigmentation
- Pallor
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- Stomach pain
- Vomiting/diarrhea
- Coughing
- Yellow skin (jaundice)
- Fever
- Chills
- Metallic taste
- Soreness of muscles
- No urine output
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Calcium
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- Muscle cramps
- Convulsions
- Lethargy
- Abnormal heart rhythm
- Decreased bone density
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- Constipation
- Kidney stones
- High doses may interact with iron and copper
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